2-Phenylpropionic acid (also known as Hydratropic acid or alpha-Methylbenzeneacetic Acid)
Applications
2-Phenylpropionic acid is a significant chemical intermediate, particularly in the pharmaceutical industry.2 Its applications include
Key applications include:
Diphenylacetonitrile is a versatile organic compound primarily used as a chemical intermediate in various industries, including pharmaceuticals, agrochemicals, and other specialty chemical sectors.
1. Pharmaceutical Intermediates
It is a key building block for the synthesis of various non-steroidal anti-inflammatory drugs (NSAIDs) that belong to the 2-arylpropionic acid class.
It is a crucial intermediate in the synthesis of Loxoprofen Sodium, a potent NSAID used for its analgesic, anti-inflammatory, and antirheumatic effects.
It is also related to the synthesis of other well-known NSAIDs like Ibuprofen and Ketoprofen, though it is not always a direct precursor for all of them.
2. Chiral Auxiliaries and Resolution
Due to its chiral nature, its enantiomers (especially (S)-(+)-2-Phenylpropionic acid) are used in asymmetric synthesis and as chiral resolving agents to separate enantiomers of other compounds.
3. Fine Chemicals
Used in the synthesis of other fine chemicals where a phenylpropionic acid moiety is desired.
Product Information
CAS Number
492-37-5 (for the racemic mixture, DL-2-Phenylpropionic acid)