- Schedule. Mon - Sat 10.00 - 18.00
4-Bromo-2,2-Diphenyl Butyronitrile
4-Bromo-2,2-Diphenyl Butyronitrile
Applications
4-Bromo-2,2-Diphenyl Butyronitrile is primarily used as a crucial chemical intermediate in the pharmaceutical industry, particularly in the synthesis of certain analgesic and antispasmodic drugs.
Key applications include
1. Pharmaceutical Synthesis (Intermediate for Loperamide and Analogs)
Its most significant application is as a key building block for the synthesis of Loperamide, an opioid-receptor agonist used as an anti-diarrheal medication. It is also used in the synthesis of other Loperamide analogs and related compounds that target μ-opioid receptors.
2. Synthesis of Antispasmodics
It serves as an intermediate in the preparation of antispasmodic drugs, such as Darifenacin (used for overactive bladder) and Imidafenacin.
3. Research and Development
It is widely used in medicinal chemistry research for the synthesis of novel compounds with potential pharmacological activities, particularly those acting on the nervous system or gastrointestinal tract. The presence of the bromine atom makes it a versatile intermediate for further functionalization through nucleophilic displacement reactions.
4. Organic Synthesis
As a versatile bromo-nitrile compound, it is utilized in various organic synthesis reactions as a building block for more complex organic molecules.
Product Information
CAS Number
39186-58-8
Related Products
Social Links
Completely synergize resource taxing.