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N,N-Dimethyl amino isopropyl chloride HCl
N,N-Dimethyl amino isopropyl chloride HCl
N,N-Dimethylamino-2-chloropropane hydrochloride (also known as N,N-Dimethylamino isopropyl chloride HCl or 2-Chloro-N,N-dimethylpropylamine hydrochloride)
Applications
N,N-Dimethylamino-2-chloropropane hydrochloride is a crucial pharmaceutical intermediate and a versatile building block in organic synthesis, particularly for the creation of various active pharmaceutical ingredients (APIs).
Key applications include:
1. Pharmaceutical Synthesis
It is a key intermediate in the manufacturing of several drugs, including:
Methadone:
A synthetic opioid used as an analgesic and in the treatment of opioid dependence.
Isothipendyl:
An antihistamine with sedative properties.
Promethazine:
An antihistamine with sedative, antiemetic, and antipsychotic effects.
2. UV Filter / UV Absorber
Due to its strong UV absorption properties, it is incorporated into various materials to protect them from degradation caused by UV radiation.
It is also used in the synthesis of analogues of lipophilic chalcones, which have shown promise as antitubercular agents. This highlights its role in the development of new treatments for tuberculosis.
3. Organic Synthesis
As a versatile ketone with a biphenyl moiety, it serves as a valuable building block in general organic synthesis for the creation of more complex organic molecules, including pharmaceuticals and other fine chemicals.
As a chlorinated tertiary amine hydrochloride, it is a versatile reagent in various organic synthesis reactions.7 The chlorine atom is a good leaving group, enabling reactions like alkylation, acylation, and reductive amination to form a wide range of organic compounds.
The amine group can undergo quaternization to form quaternary ammonium salts, which are used as phase-transfer catalysts, surfactants, and ion-exchange materials.
4. Research & Development
It is widely utilized in medicinal chemistry and academic research as a building block for exploring novel chemical entities with potential biological activities.
Product Information
CAS Number
4584-49-0
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